Exoc4 - exocyst complex component 4 Gene

Also Known as Sec8; Sec8l1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20336

Summary

Enables PDZ domain binding activity. Involved in cilium assembly and protein localization to ciliary membrane. Acts upstream of or within paraxial mesoderm formation. Located in growth cone membrane; microvillus; and myelin sheath abaxonal region. Is expressed in several structures, including central nervous system; extraembryonic component; ganglia; and retina. Orthologous to human EXOC4 (exocyst complex component 4). [provided by Alliance of Genome Resources, Apr 2022]

Exoc4 Products (2)

mRNA Protein Name
NM_001347089.2 NP_001334018.1 exocyst complex component 4 isoform 2
NM_009148.4 NP_033174.2 exocyst complex component 4 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables PDZ domain binding IPI
IPI: Inferred from physical interaction
12738960 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
16601687 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within paraxial mesoderm formation IMP
IMP: Inferred from mutant phenotype
9441674 MGI
acts upstream of or within protein transmembrane transport IMP
IMP: Inferred from mutant phenotype
28576874 MGI
Cellular Component GO Annotation Evidence References Source
located in growth cone membrane IDA
IDA: Inferred from direct assay
21389209 MGI
located in microvillus IDA
IDA: Inferred from direct assay
19587293 MGI
located in myelin sheath abaxonal region IDA
IDA: Inferred from direct assay
20237282 MGI
located in neuron projection IDA
IDA: Inferred from direct assay
19587293 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

exocyst complex component 4

  • SEC8-like 1

  • exocyst complex component Sec8

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04590 EXOC4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Exoc4 NCBI NCBI:60412