Slc12a4 - solute carrier family 12, member 4 Gene

Also Known as KCC1; RBCKCC1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20498

Summary

Predicted to enable potassium:chloride symporter activity and protein kinase binding activity. Predicted to be involved in several processes, including cell volume homeostasis; inorganic ion homeostasis; and inorganic ion transmembrane transport. Predicted to act upstream of or within potassium ion transport. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in several structures, including adrenal gland; genitourinary system; liver; retina; and spleen. Orthologous to human SLC12A4 (solute carrier family 12 member 4). [provided by Alliance of Genome Resources, Apr 2022]

Slc12a4 Products (2)

mRNA Protein Name
NM_001253804.1 NP_001240733.1 solute carrier family 12 member 4 isoform 1
NM_009195.3 NP_033221.1 solute carrier family 12 member 4 isoform 2
Molecular Function GO Annotation Evidence References Source
enables potassium:chloride symporter activity IDA
IDA: Inferred from direct assay
11551954 MGI
Biological Process GO Annotation Evidence References Source
involved in potassium ion transmembrane transport IDA
IDA: Inferred from direct assay
11551954 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

solute carrier family 12 member 4

  • K-Cl Co-transporter-1

  • K-Cl cotransporter KCC1

  • electroneutral potassium-chloride cotransporter 1

  • erythroid K-Cl cotransporter 1

  • mKCC1

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc12a4 NCBI NCBI:6560