MTLN - mitoregulin Gene

Also Known as MPM; LEMP; MOXI; SMIM37; LINC00116; NCRNA00116

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 205251

About MTLN

This gene has 3 transcripts (splice variants) and 137 orthologues. Ubiquitous expression in fat (RPKM 3.7), kidney (RPKM 3.7) and 25 other tissues.

Summary

Involved in several processes, including fatty acid beta-oxidation; positive regulation of mitochondrial membrane potential; and triglyceride homeostasis. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]

MTLN Products (1)

mRNA Protein Name
NM_001384134.1 NP_001371063.1 mitoregulin

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32243843 GOA
Biological Process GO Annotation Evidence References Source
involved in fatty acid beta-oxidation IMP
IMP: Inferred from mutant phenotype
32243843 GOA
involved in positive regulation of mitochondrial membrane potential IDA
IDA: Inferred from direct assay
29949756 GOA
involved in positive regulation of sequestering of calcium ion IDA
IDA: Inferred from direct assay
29949756 GOA
involved in triglyceride homeostasis IMP
IMP: Inferred from mutant phenotype
32243843 GOA
Cellular Component GO Annotation Evidence References Source
located in mitochondrion IDA
IDA: Inferred from direct assay
32243843 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mitoregulin

  • lncRNA encoded micropeptide

Related Diseases

Diseases Alias
Joubert Syndrome 4

  • JBTS4

  • Joubert Syndrome With Renal Defect

  • Joubert Syndrome With Renal Anomalies

  • Js-R

  • Joubert Syndrome, Type 4
Nephronophthisis 1

  • NPHP1

  • Nephronophthisis, Familial Juvenile

  • Nph1

  • Nephronophthisis 1, Juvenile

  • Juvenile Nephronophthisis 1

  • Familial Juvenile Nephronophthisis 1

  • Nephronophthisis, Type 1
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08783 MTLN Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus MTLN MGD MGI:1915135
Rattus norvegicus MTLN RGD RGD:10401149