Slc3a1 - solute carrier family 3, member 1 Gene

Also Known as D2H; NBAT; NTAA; RBAT

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20532

Summary

Enables protein heterodimerization activity. Involved in amino acid transport and gene expression. Located in apical plasma membrane and brush border membrane. Is expressed in several structures, including brain; genitourinary system; integumental system; intestine; and respiratory system. Used to study cystinuria. Human ortholog(s) of this gene implicated in cystinuria. Orthologous to human SLC3A1 (solute carrier family 3 member 1). [provided by Alliance of Genome Resources, Apr 2022]

Slc3a1 Products (1)

mRNA Protein Name
NM_009205.2 NP_033231.2 neutral and basic amino acid transport protein rBAT

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
12167606 MGI
enables protein heterodimerization activity IPI
IPI: Inferred from physical interaction
26739563 MGI
Biological Process GO Annotation Evidence References Source
involved in L-cystine transport IDA
IDA: Inferred from direct assay
26739563 MGI
involved in L-glutamate transmembrane transport IDA
IDA: Inferred from direct assay
26739563 MGI
involved in aspartate transmembrane transport IDA
IDA: Inferred from direct assay
26739563 MGI
involved in gene expression IMP
IMP: Inferred from mutant phenotype
26739563 MGI
Cellular Component GO Annotation Evidence References Source
is active in apical plasma membrane IPI
IPI: Inferred from physical interaction
26739563 MGI
located in brush border membrane IDA
IDA: Inferred from direct assay
12167606 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

neutral and basic amino acid transport protein rBAT

  • b(0,+)-type amino acid transport protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13241 SLC3A1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc3a1 NCBI NCBI:6519