Sox12 - SRY (sex determining region Y)-box 12 Gene

Also Known as 2010205A02Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20667

Summary

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and transcription cis-regulatory region binding activity. Involved in positive regulation of regulatory T cell differentiation; positive regulation of transcription by RNA polymerase II; and spinal cord development. Part of protein-DNA complex. Is expressed in alimentary system; brain; cranial ganglion; genitourinary system; and neural retina. Orthologous to human SOX12 (SRY-box transcription factor 12). [provided by Alliance of Genome Resources, Apr 2022]

Sox12 Products (1)

mRNA Protein Name
NM_011438.2 NP_035568.1 transcription factor SOX-12

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables DNA binding IDA
IDA: Inferred from direct assay
18403418 MGI
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
18505825 MGI
enables transcription cis-regulatory region binding IDA
IDA: Inferred from direct assay
18505825 MGI
Biological Process GO Annotation Evidence References Source
involved in positive regulation of regulatory T cell differentiation IMP
IMP: Inferred from mutant phenotype
30190287 MGI
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
18403418 MGI
involved in spinal cord development IDA
IDA: Inferred from direct assay
18505825 MGI
Cellular Component GO Annotation Evidence References Source
part of protein-DNA complex IDA
IDA: Inferred from direct assay
18505825 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transcription factor SOX-12

  • SRY-box containing gene 12

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13585 SOX12 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sox12 NCBI NCBI:6666