Serpinb6a - serine (or cysteine) peptidase inhibitor, clade B, member 6a Gene

Also Known as PI-6; Spi3; Serpinb6; ovalbumin; 4930482L21Rik; D330015H01Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20719

Summary

Predicted to enable protease binding activity and serine-type endopeptidase inhibitor activity. Predicted to be involved in cellular response to osmotic stress; negative regulation of endopeptidase activity; and sensory perception of sound. Predicted to act upstream of or within negative regulation of peptidase activity. Located in cytoplasm. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; inner ear; and respiratory system. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 91. Orthologous to human SERPINB6 (Serpin family B member 6). [provided by Alliance of Genome Resources, Apr 2022]

Serpinb6a Products (4)

mRNA Protein Name
NM_001164117.1 NP_001157589.1 serpin B6 isoform a
NM_001164118.1 NP_001157590.1 serpin B6 isoform b
NM_001243192.1 NP_001230121.1 serpin B6 isoform b
NM_009254.3 NP_033280.1 serpin B6 isoform b

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
7608171 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
17761692 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

serpin B6

  • placental thrombin inhibitor

  • serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 6

  • serine (or cysteine) proteinase inhibitor, clade B, member 6a

  • serine protease inhibitor 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12714 SERPINB6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown