Stxbp5l - syntaxin binding protein 5-like Gene

Also Known as LLGL4; T2dm1; t2md1; tomosyn-2; 9430094L02; A830015P08Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 207227

Summary

Enables syntaxin binding activity. Involved in regulation of synaptic vesicle exocytosis. Acts upstream of or within glucose homeostasis and regulation of secretion by cell. Located in plasma membrane. Is active in neuromuscular junction and neuronal dense core vesicle. Is expressed in several structures, including alimentary system; brain; male reproductive gland or organ; spinal cord; and trigeminal nerve. Orthologous to human STXBP5L (syntaxin binding protein 5L). [provided by Alliance of Genome Resources, Apr 2022]

Stxbp5l Products (4)

mRNA Protein Name
NM_001114611.1 NP_001108083.1 syntaxin-binding protein 5-like isoform s
NM_001114612.1 NP_001108084.1 syntaxin-binding protein 5-like isoform b
NM_001114613.1 NP_001108085.1 syntaxin-binding protein 5-like isoform m
NM_172440.3 NP_766028.2 syntaxin-binding protein 5-like isoform xb

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within glucose homeostasis IMP
IMP: Inferred from mutant phenotype
21998599 MGI
acts upstream of or within negative regulation of insulin secretion IDA
IDA: Inferred from direct assay
21998599 MGI
acts upstream of or within regulation of exocytosis IDA
IDA: Inferred from direct assay
21330375 MGI
involved in regulation of synaptic vesicle exocytosis EXP
EXP: Inferred from Experiment
24744148 MGI
involved in regulation of synaptic vesicle exocytosis IDA
IDA: Inferred from direct assay
24744148 MGI
involved in regulation of synaptic vesicle exocytosis IMP
IMP: Inferred from mutant phenotype
24744148 MGI
Cellular Component GO Annotation Evidence References Source
is active in neuromuscular junction EXP
EXP: Inferred from Experiment
24744148 MGI
is active in neuromuscular junction IDA
IDA: Inferred from direct assay
24744148 MGI
is active in neuromuscular junction IMP
IMP: Inferred from mutant phenotype
24744148 MGI
is active in neuronal dense core vesicle IDA
IDA: Inferred from direct assay
28746398 MGI
is active in neuronal dense core vesicle IEP
IEP: Inferred from expression pattern
28746398 MGI
is active in neuronal dense core vesicle IMP
IMP: Inferred from mutant phenotype
28746398 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

syntaxin-binding protein 5-like

  • insulin level locus 1

  • lethal(2) giant larvae protein homolog 4

  • tomosyn 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13994 STXBP5L Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Stxbp5l NCBI NCBI:9515