Serpinb5 - serine (or cysteine) peptidase inhibitor, clade B, member 5 Gene

Also Known as PI-5; Spi7; Maspin; ovalbumin; 1110036M19Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20724

Summary

Predicted to enable serine-type endopeptidase inhibitor activity. Acts upstream of or within several processes, including extracellular matrix organization; prostate gland morphogenesis; and regulation of epithelial cell proliferation. Located in cytoplasm. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; respiratory system; and sensory organ. Orthologous to human SERPINB5 (Serpin family B member 5). [provided by Alliance of Genome Resources, Apr 2022]

Serpinb5 Products (3)

mRNA Protein Name
NM_001360853.1 NP_001347782.1 serpin B5 isoform a
NM_001360854.1 NP_001347783.1 serpin B5 isoform b
NM_009257.4 NP_033283.1 serpin B5 isoform a

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within extracellular matrix organization IMP
IMP: Inferred from mutant phenotype
18593913 MGI
acts upstream of or within morphogenesis of an epithelium IMP
IMP: Inferred from mutant phenotype
18593913 MGI
acts upstream of or within prostate gland morphogenesis IMP
IMP: Inferred from mutant phenotype
18593913 MGI
acts upstream of or within regulation of epithelial cell proliferation IMP
IMP: Inferred from mutant phenotype
18593913 MGI
Cellular Component GO Annotation Evidence References Source
is active in cornified envelope IDA
IDA: Inferred from direct assay
26644517 MGI
located in cytoplasm IDA
IDA: Inferred from direct assay
18593913 MGI
located in sarcoplasm IDA
IDA: Inferred from direct assay
18593913 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

serpin B5

  • peptidase inhibitor 5

  • protease inhibitor 5

  • serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 5

  • serine (or cysteine) proteinase inhibitor, clade B, member 5

  • serine protease inhibitor 7

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12713 SERPINB5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20229 Serpinb5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26736 Serpinb5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Serpinb5 NCBI NCBI:5268