2. Gene
  3. Shroom4 - shroom family member 4 Gene

Shroom4 - shroom family member 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Gm724; Shrm4; D430043L16Rik

Gene ID: 208431 | Gene type: protein coding

About Shroom4

Summary

Enables actin filament binding activity and Myosin II binding activity. Acts upstream of or within actin filament organization. Located in several cellular components, including apical plasma membrane; basal plasma membrane; and stress fiber. Colocalizes with cortical actin Cytoskeleton. Is expressed in several structures, including brain; genitourinary system; heart; liver; and lung. Human ortholog(s) of this gene implicated in Stocco Dos Santos type X-linked intellectual disability. Orthologous to human SHROOM4 (shroom family member 4). [provided by Alliance of Genome Resources, Apr 2022]

Shroom4 Products(3)

mRNA Protein Name
NM_001040459.2 NP_001035549.1 protein Shroom4 isoform 1
NM_001313764.1 NP_001300693.1 protein Shroom4 isoform 2
NM_001313765.1 NP_001300694.1 protein Shroom4 isoform 3
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables actin filament binding IDA
IDA: Inferred from direct assay
17009331 MGI
enables myosin II binding IDA
IDA: Inferred from direct assay
17009331 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within actin filament organization IDA
IDA: Inferred from direct assay
17009331 MGI
Cellular Component GO Annotation Evidence Reference Source
located in actin cytoskeleton IDA
IDA: Inferred from direct assay
17009331 MGI
located in apical plasma membrane IDA
IDA: Inferred from direct assay
17009331 MGI
located in basal plasma membrane IDA
IDA: Inferred from direct assay
17009331 MGI
colocalizes with cortical actin cytoskeleton IDA
IDA: Inferred from direct assay
16684770 MGI
located in cytoplasm IDA
IDA: Inferred from direct assay
17009331 MGI
located in stress fiber IDA
IDA: Inferred from direct assay
17009331 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein Shroom4

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12887 SHROOM4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Shroom4 NCBI NCBI:57477