Creb3l2 - cAMP responsive element binding protein 3-like 2 Gene

Mus musculus

Also known as BBF2H7; SCIRR69; C530025K05Rik

Gene ID: 208647 | Gene type: protein coding

About Creb3l2

Summary

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and cAMP response element binding activity. Involved in chondrocyte differentiation; endoplasmic reticulum to Golgi vesicle-mediated transport; and positive regulation of transcription by RNA polymerase II. Predicted to be located in chromatin; nucleoplasm; and perinuclear endoplasmic reticulum. Is expressed in several structures, including brain; early conceptus; embryo mesenchyme; and genitourinary system. Orthologous to human CREB3L2 (cAMP responsive element binding protein 3 like 2). [provided by Alliance of Genome Resources, Apr 2022]

Creb3l2 Products(1)

mRNA	Protein	Name
NM_178661.4	NP_848776.2	cyclic AMP-responsive element-binding protein 3-like protein 2

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables DNA-binding transcription activator activity, RNA polymerase II-specific	IDA IDA: Inferred from direct assay	17178827	MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA IDA: Inferred from direct assay	17178827	MGI
enables cAMP response element binding	IMP IMP: Inferred from mutant phenotype	19767744	MGI
enables transcription cis-regulatory region binding	IMP IMP: Inferred from mutant phenotype	19767744	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in cartilage development	IMP IMP: Inferred from mutant phenotype	19767744	MGI
involved in chondrocyte differentiation	IMP IMP: Inferred from mutant phenotype	19767744	MGI
involved in endoplasmic reticulum to Golgi vesicle-mediated transport	IMP IMP: Inferred from mutant phenotype	19767744	MGI
involved in positive regulation of DNA-templated transcription	IDA IDA: Inferred from direct assay	19767744	MGI
involved in positive regulation of transcription by RNA polymerase II	IDA IDA: Inferred from direct assay	17178827	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

cyclic AMP-responsive element-binding protein 3-like protein 2

cAMP-responsive element-binding protein 3-like protein 2

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS03151	CREB3L2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Creb3l2	NCBI	NCBI:64764

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