Supt6 - SPT6, histone chaperone and transcription elongation factor Gene

Also Known as SPT6; Supt6h; mKIAA0162; 5131400N11Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20926

Summary

Predicted to enable histone binding activity and nucleosome binding activity. Involved in several processes, including negative regulation of histone H3-K27 methylation; regulation of mRNA export from nucleus; and regulation of nucleobase-containing compound metabolic process. Acts upstream of or within blastocyst formation. Predicted to be located in nucleus. Predicted to be part of transcription elongation factor complex. Predicted to be active in transcriptionally active chromatin. Is expressed in several structures, including brain; early conceptus; genitourinary system; liver; and spleen. Orthologous to human SUPT6H (SPT6 homolog, histone chaperone and transcription elongation factor). [provided by Alliance of Genome Resources, Apr 2022]

Supt6 Products (1)

mRNA Protein Name
NM_009297.2 NP_033323.2 transcription elongation factor SPT6

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
17234882 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within blastocyst formation IMP
IMP: Inferred from mutant phenotype
27869233 MGI
involved in positive regulation of transcription elongation by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
17234882 MGI
involved in regulation of isotype switching IMP
IMP: Inferred from mutant phenotype
21518874 MGI
involved in regulation of mRNA export from nucleus IMP
IMP: Inferred from mutant phenotype
17234882 MGI
involved in regulation of mRNA processing IMP
IMP: Inferred from mutant phenotype
17234882 MGI
involved in regulation of muscle cell differentiation IMP
IMP: Inferred from mutant phenotype
23503590 MGI
involved in transcription elongation-coupled chromatin remodeling IMP
IMP: Inferred from mutant phenotype
23503590 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transcription elongation factor SPT6

  • suppressor of Ty 6 homolog

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14039 SUPT6H Human Pre-designed siRNA Set A Pre-designed Set / Unkown