2. Gene
  3. Eif2b1 - eukaryotic translation initiation factor 2B, subunit 1 (alpha) Gene

Eif2b1 - eukaryotic translation initiation factor 2B, subunit 1 (alpha) Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as EIF2BA; D5Ertd406e

Gene ID: 209354 | Gene type: protein coding

About Eif2b1

Summary

This gene encodes the alpha subunit of the eukaryotic translation initiation factor complex 2B (eIF2B). The eIF2B complex is a heterodecamer comprised of two molecules each of alpha, beta, gamma, delta and epsilon subunits. The eIF2B complex is a critical regulator of protein synthesis acting as the guanine nucleotide exchange factor for eIF2 to enable the formation of ternary complex that is required for the initiation of mRNA translation. [provided by RefSeq, Aug 2015]

Eif2b1 Products(1)

mRNA Protein Name
NM_145371.4 NP_663346.1 translation initiation factor eIF-2B subunit alpha
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
15752756 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

translation initiation factor eIF-2B subunit alpha

eIF-2B GDP-GTP exchange factor subunit alpha

eukaryotic translation initiation factor 2B, subunit 1 (alpha, 26kDa)

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04248 EIF2B1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Eif2b1 NCBI NCBI:1967