2. Gene
  3. Trp53bp2 - transformation related protein 53 binding protein 2 Gene

Trp53bp2 - transformation related protein 53 binding protein 2 Gene

  • Gene
  • Protein
  • Agent
Mus musculus

Also known as 53BP2; ASPP2; Tp53bp2; PPP1R13A

Gene ID: 209456 | Gene type: protein coding

About Trp53bp2

Summary

Predicted to enable NF-kappaB binding activity; identical protein binding activity; and p53 binding activity. Acts upstream of or within several processes, including embryo development; heart development; and response to ionizing radiation. Predicted to be located in cell junction and cytosol. Predicted to be active in nucleus. Predicted to colocalize with perinuclear region of cytoplasm. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Used to study chromosome 1q41-q42 deletion syndrome. Orthologous to human TP53BP2 (tumor protein p53 binding protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Trp53bp2 Products(2)

mRNA Protein Name
NM_173378.2 NP_775554.2 apoptosis-stimulating of p53 protein 2
NM_173378.2 NP_775554.2 apoptosis-stimulating of p53 protein 2
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within central nervous system development IMP
IMP: Inferred from mutant phenotype
16702401 MGI
acts upstream of or within embryo development ending in birth or egg hatching IGI
IGI: Inferred from genetic interaction
16702401 MGI
acts upstream of or within heart development IMP
IMP: Inferred from mutant phenotype
16702401 MGI
acts upstream of or within response to ionizing radiation IMP
IMP: Inferred from mutant phenotype
16702401 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

apoptosis-stimulating of p53 protein 2

p53-binding protein 2

p53BP2

tumor protein p53 binding protein, 2

tumor suppressor p53-binding protein 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14916 TP53BP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown