2. Gene
  3. Hsh2d - hematopoietic SH2 domain containing Gene

Hsh2d - hematopoietic SH2 domain containing Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as ALX; Hsh2

Gene ID: 209488 | Gene type: protein coding

About Hsh2d

Summary

Enables protein-macromolecule adaptor activity. Acts upstream of or within T cell activation; negative regulation of B cell apoptotic process; and negative regulation of mitochondrial depolarization. Located in cytosol and mitochondrion. Is expressed in spleen and thymus. Orthologous to human HSH2D (hematopoietic SH2 domain containing). [provided by Alliance of Genome Resources, Apr 2022]

Hsh2d Products(1)

mRNA Protein Name
NM_197944.1 NP_922935.1 hematopoietic SH2 domain-containing protein
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein-macromolecule adaptor activity IDA
IDA: Inferred from direct assay
12960172 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within T cell activation IDA
IDA: Inferred from direct assay
12960172 MGI
acts upstream of or within negative regulation of B cell apoptotic process IDA
IDA: Inferred from direct assay
15569688 MGI
acts upstream of or within negative regulation of mitochondrial depolarization IDA
IDA: Inferred from direct assay
15569688 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cytosol IDA
IDA: Inferred from direct assay
15569688 MGI
located in mitochondrion IDA
IDA: Inferred from direct assay
15569688 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

hematopoietic SH2 domain-containing protein

adaptor in lymphocytes of unknown function X

adaptor protein ALx2

hematopoietic SH2 protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06414 HSH2D Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hsh2d NCBI NCBI:84941