Frmd4a - FERM domain containing 4A Gene

Also Known as Frmd4; Gm13190; mKIAA1294; 5330420J21; 2700017I06Rik; C230040M21Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 209630

Summary

Enables protein-macromolecule adaptor activity. Involved in negative regulation of protein secretion. Acts upstream of or within establishment of epithelial cell polarity. Located in bicellular tight junction. Is expressed in cerebral cortex; ganglia; heart; paraxial mesenchyme; and thymus primordium. Orthologous to human FRMD4A (FERM domain containing 4A). [provided by Alliance of Genome Resources, Apr 2022]

Frmd4a Products (4)

mRNA Protein Name
NM_001177843.1 NP_001171314.1 FERM domain-containing protein 4A isoform 2
NM_001177844.1 NP_001171315.1 FERM domain-containing protein 4A isoform 3
NM_001347086.1 NP_001334015.1 FERM domain-containing protein 4A isoform 4
NM_172475.3 NP_766063.3 FERM domain-containing protein 4A isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein-macromolecule adaptor activity IPI
IPI: Inferred from physical interaction
20080746 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within establishment of epithelial cell polarity IGI
IGI: Inferred from genetic interaction
20080746 MGI
involved in negative regulation of protein secretion IMP
IMP: Inferred from mutant phenotype
27044754 MGI
Cellular Component GO Annotation Evidence References Source
located in bicellular tight junction IDA
IDA: Inferred from direct assay
20080746 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

FERM domain-containing protein 4A

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05101 FRMD4A Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Frmd4a NCBI NCBI:55691