2. Gene
  3. Synj2 - synaptojanin 2 Gene

Synj2 - synaptojanin 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as SJ2; mKIAA0348

Gene ID: 20975 | Gene type: protein coding

About Synj2

Summary

Enables phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity. Predicted to be involved in several processes, including dephosphorylation; intracellular distribution of mitochondria; and synaptic vesicle endocytosis. Predicted to be located in axon terminus; cytoplasmic microtubule; and ruffle membrane. Predicted to be extrinsic component of mitochondrial outer membrane. Predicted to be active in perinuclear region of cytoplasm and presynapse. Is expressed in several structures, including alimentary system; genitourinary system; liver; nose; and spleen. Orthologous to human SYNJ2 (synaptojanin 2). [provided by Alliance of Genome Resources, Apr 2022]

Synj2 Products(7)

mRNA Protein Name
NM_001113351.1 NP_001106822.1 synaptojanin-2 isoform d
NM_001113352.2 NP_001106823.1 synaptojanin-2 isoform b
NM_001113353.2 NP_001106824.1 synaptojanin-2 isoform a
NM_001290698.1 NP_001277627.1 synaptojanin-2 isoform e
NM_001357665.1 NP_001344594.1 synaptojanin-2 isoform f
NM_001357667.1 NP_001344596.1 synaptojanin-2 isoform g
NM_011523.2 NP_035653.2 synaptojanin-2 isoform c
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity IDA
IDA: Inferred from direct assay
9442075 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

synaptojanin-2

synaptic inositol-1,4,5-trisphosphate 5-phosphatase 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-141659 CMPD-39 99.74% Unkown
HY-141659A (R)-CMPD-39 99.78% Unkown
HY-RS14094 SYNJ2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14095 SYNJ2BP Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Synj2 NCBI NCBI:8871