1. Gene
  2. Tbc1d4 - TBC1 domain family, member 4 Gene

Tbc1d4 - TBC1 domain family, member 4 Gene

Mus musculus

Also known as As160; A930035N22; 5930406J04Rik

Gene ID: 210789 | Gene type: protein coding

About Tbc1d4

Summary

Predicted to enable GTPase activator activity. Predicted to be involved in several processes, including activation of GTPase activity; intracellular protein transport; and negative regulation of vesicle fusion. Predicted to act upstream of or within cellular response to Insulin stimulus. Predicted to be located in cytosol and vesicle. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; hemolymphoid system gland; and respiratory system. Human ortholog(s) of this gene implicated in acanthosis nigricans. Orthologous to human TBC1D4 (TBC1 domain family member 4). [provided by Alliance of Genome Resources, Apr 2022]

Tbc1d4 Products(5)

mRNA Protein Name
NM_001081278.3 NP_001074747.2 TBC1 domain family member 4 isoform 3
NM_001404671.1 NP_001391600.1 TBC1 domain family member 4 isoform 1
NM_001404672.1 NP_001391601.1 TBC1 domain family member 4 isoform 2
NM_001404673.1 NP_001391602.1 TBC1 domain family member 4 isoform 4
NM_001404674.1 NP_001391603.1 TBC1 domain family member 4 isoform 5
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within cellular response to insulin stimulus IGI
IGI: Inferred from genetic interaction
24349514 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

TBC1 domain family member 4

akt substrate of 160 kDa

Orthologs Information

Species Symbol Source ID
Homo sapiens Tbc1d4 NCBI NCBI:9882