Arfgef1 - ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited) Gene

Mus musculus

Also known as BIG1; P200; ARFGEP1; D130059B05Rik; D730028O18Rik

Gene ID: 211673 | Gene type: protein coding

About Arfgef1

Summary

Predicted to enable guanyl-nucleotide exchange factor activity; Myosin binding activity; and protein kinase A regulatory subunit binding activity. Predicted to be involved in several processes, including negative regulation of GTPase activity; positive regulation of protein glycosylation in Golgi; and positive regulation of protein kinase B signaling. Predicted to act upstream of or within protein transport. Predicted to be located in several cellular components, including Golgi apparatus; nuclear lumen; and perinuclear region of cytoplasm. Predicted to be part of small nuclear ribonucleoprotein complex. Is expressed in brain. Orthologous to human ARFGEF1 (ADP ribosylation factor guanine nucleotide exchange factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Arfgef1 Products(1)

mRNA	Protein	Name
NM_001102430.1	NP_001095900.1	brefeldin A-inhibited guanine nucleotide-exchange protein 1

Protein Preferred Names

Protein Names

brefeldin A-inhibited guanine nucleotide-exchange protein 1

ADP-ribosylation factor guanine nucleotide-exchange factor 1

brefeldin A-inhibited GEP 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00902	ARFGEF1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Arfgef1	NCBI	NCBI:10565

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