Arfgef1 - ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited) Gene

Predicted to enable guanyl-nucleotide exchange factor activity; Myosin binding activity; and protein kinase A regulatory subunit binding activity. Predicted to be involved in several processes, including negative regulation of GTPase activity; positive regulation of protein glycosylation in Golgi; and positive regulation of protein kinase B signaling. Predicted to act upstream of or within protein transport. Predicted to be located in several cellular components, including Golgi apparatus; nuclear lumen; and perinuclear region of cytoplasm. Predicted to be part of small nuclear ribonucleoprotein complex. Is expressed in brain. Orthologous to human ARFGEF1 (ADP ribosylation factor guanine nucleotide exchange factor 1). [provided by Alliance of Genome Resources, Apr 2022]