2. Gene
  3. Syne3 - spectrin repeat containing, nuclear envelope family member 3 Gene

Syne3 - spectrin repeat containing, nuclear envelope family member 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as KASH3; nesprin-3

Gene ID: 212073 | Gene type: protein coding

About Syne3

Summary

Predicted to enable actin filament binding activity and cytoskeleton-nuclear membrane anchor activity. Predicted to be involved in several processes, including establishment of protein localization to membrane; nuclear migration; and regulation of cell shape. Located in nuclear outer membrane. Part of meiotic nuclear membrane microtubule tethering complex. Is expressed in several structures, including adipose tissue; alimentary system; genitourinary system; hemolymphoid system gland; and nervous system. Orthologous to human SYNE3 (spectrin repeat containing nuclear envelope family member 3). [provided by Alliance of Genome Resources, Apr 2022]

Syne3 Products(3)

mRNA Protein Name
NM_001042699.3 NP_001036164.1 nesprin-3 isoform alpha
NM_001403458.1 NP_001390387.1 nesprin-3 isoform alpha
NM_172500.4 NP_766088.2 nesprin-3 isoform beta
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
18638474 MGI
Cellular Component GO Annotation Evidence Reference Source
part of meiotic nuclear membrane microtubule tethering complex IDA
IDA: Inferred from direct assay
20711465 MGI
located in nuclear outer membrane IDA
IDA: Inferred from direct assay
18396275 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

nesprin-3

KASH domain-containing protein 3

nuclear envelope spectrin repeat protein 3

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14087 SYNE3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Syne3 NCBI NCBI:161176