Gsap - gamma-secretase activating protein Gene

Also Known as Pion; A530088I07Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 212167

Summary

Predicted to enable amyloid-beta binding activity. Involved in positive regulation of amyloid-beta formation. Predicted to be located in Golgi apparatus. Predicted to be active in trans-Golgi network. Is expressed in brain ventricular layer. Orthologous to human GSAP (gamma-secretase activating protein). [provided by Alliance of Genome Resources, Apr 2022]

Gsap Products (3)

mRNA Protein Name
NM_001359876.2 NP_001346805.1 gamma-secretase-activating protein isoform 2
NM_001359877.2 NP_001346806.1 gamma-secretase-activating protein isoform 3
NM_175437.4 NP_780646.2 gamma-secretase-activating protein isoform 1

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in positive regulation of amyloid-beta formation IDA
IDA: Inferred from direct assay
20811458 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

gamma-secretase-activating protein

  • pigeon homolog

  • protein pigeon homolog

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05851 GSAP Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gsap NCBI NCBI:54103