EVI2B - ecotropic viral integration site 2B Gene

Also Known as EVDB; CD361; D17S376

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 2124

About EVI2B

Cytogenetic location: 17q11.2 Genomic coordinates (GRCh38): 17:31,303,770-31,314,054 (from NCBI)

This gene has 2 transcripts (splice variants) and 89 orthologues. Broad expression in lymph node (RPKM 78.2), spleen (RPKM 77.3) and 15 other tissues.

Summary

Involved in positive regulation of granulocyte differentiation. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

EVI2B Products (1)

mRNA Protein Name
NM_006495.4 NP_006486.3 protein EVI2B precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
Biological Process GO Annotation Evidence References Source
involved in positive regulation of granulocyte differentiation IMP
IMP: Inferred from mutant phenotype
28186500 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein EVI2B

  • EVI-2B

EVI2B Antibodies

Cat. No. Product Name Application Reactivity
HY-P84268 CD361 Antibody (YA3965) WB, FC, ELISA Human
HY-P84268A CD361 Antibody (YA3965)(PBS only) WB, FC, ELISA Human

Related Diseases

Diseases Alias
Chromosome 17q11.2 Deletion Syndrome

  • Nf1 Microdeletion Syndrome

  • 17q11 Microdeletion Syndrome

  • Neurofibromatosis Type 1 Microdeletion Syndrome

  • Van Asperen Syndrome

  • Del(17)(Q11)

  • Monosomy 17q11

  • Chromosome 17q11.2 Deletion Syndrome, 1.4mb
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04575 EVI2B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20921 Evi2b Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27438 Evi2b Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus EVI2B MGD MGI:1890682
Felis catus EVI2B VGNC VGNC:98949
Canis familiaris EVI2B VGNC VGNC:53237
Rattus norvegicus EVI2B RGD RGD:6495961
Bos taurus EVI2B VGNC VGNC:55822
Others EVI2B NCBI