Mars2 - methionine-tRNA synthetase 2 (mitochondrial) Gene

Mus musculus

Also known as MetRS; C730026E21Rik

Gene ID: 212679 | Gene type: protein coding

About Mars2

Summary

Predicted to enable methionine-tRNA Ligase activity. Predicted to be involved in methionyl-tRNA aminoacylation. Predicted to act upstream of or within translation. Located in mitochondrion. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and immune system. Human ortholog(s) of this gene implicated in combined Oxidative Phosphorylation deficiency 25 and spastic ataxia 3. Orthologous to human MARS2 (methionyl-tRNA synthetase 2, mitochondrial). [provided by Alliance of Genome Resources, Apr 2022]

Mars2 Products(1)

mRNA	Protein	Name
NM_175439.3	NP_780648.1	methionine--tRNA ligase, mitochondrial precursor

Protein Preferred Names

Protein Names

methionine--tRNA ligase, mitochondrial

methionine--tRNA ligase 2	methionyl-tRNA synthetase 2
methionyl-tRNA synthetase, mitochondrial	mitochondrial methionine--tRNA ligase
mitochondrial methionyl-tRNA synthetase	mtMetRS

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08154	MARS2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Mars2	NCBI	NCBI:92935

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