Tnpo2 - transportin 2 (importin 3, karyopherin beta 2b) Gene

Also Known as IPO3; TRN2; Knpb2b; Kpnb2b; 1110034O24Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 212999

Summary

Predicted to enable nuclear import signal receptor activity and nuclear localization sequence binding activity. Acts upstream of or within negative regulation of muscle cell differentiation and protein import into nucleus. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including adrenal gland; alimentary system; gallbladder; genitourinary system; and nervous system. Orthologous to human TNPO2 (transportin 2). [provided by Alliance of Genome Resources, Apr 2022]

Tnpo2 Products (7)

mRNA Protein Name
NM_001122843.2 NP_001116315.1 transportin-2 isoform 1
NM_001364031.1 NP_001350960.1 transportin-2 isoform 1
NM_001364032.1 NP_001350961.1 transportin-2 isoform 2
NM_001364033.1 NP_001350962.1 transportin-2 isoform 2
NM_001364034.1 NP_001350963.1 transportin-2 isoform 2
NM_001379096.1 NP_001366025.1 transportin-2 isoform 1
NM_145390.5 NP_663365.3 transportin-2 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
17475777 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within negative regulation of muscle cell differentiation IMP
IMP: Inferred from mutant phenotype
17475777 MGI
acts upstream of or within protein import into nucleus IMP
IMP: Inferred from mutant phenotype
17475777 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transportin-2

  • karyopherin (importin) beta 2b

  • karyopherin beta-2b

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14860 TNPO2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tnpo2 NCBI NCBI:30000