Dync2li1 - dynein cytoplasmic 2 light intermediate chain 1 Gene

Also Known as LIC3; D2lic; CGI-60; mD2LIC; 4933404O11Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 213575

Summary

Predicted to enable dynein heavy chain binding activity. Acts upstream of or within cilium assembly and determination of left/right symmetry. Located in apical part of cell; axoneme; and motile cilium. Is expressed in embryo; gut; heart; and node. Human ortholog(s) of this gene implicated in asphyxiating thoracic dystrophy. Orthologous to human DYNC2LI1 (dynein cytoplasmic 2 light intermediate chain 1). [provided by Alliance of Genome Resources, Apr 2022]

Dync2li1 Products (1)

mRNA Protein Name
NM_172256.2 NP_758460.1 cytoplasmic dynein 2 light intermediate chain 1

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within cilium assembly IMP
IMP: Inferred from mutant phenotype
15371312 MGI
acts upstream of or within determination of left/right symmetry IMP
IMP: Inferred from mutant phenotype
15371312 MGI
Cellular Component GO Annotation Evidence References Source
located in apical part of cell IDA
IDA: Inferred from direct assay
12802074 MGI
located in axoneme IDA
IDA: Inferred from direct assay
12802074 MGI
located in motile cilium IDA
IDA: Inferred from direct assay
12802074 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cytoplasmic dynein 2 light intermediate chain 1

  • dynein 2 light intermediate chain

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04087 DYNC2LI1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dync2li1 NCBI NCBI:51626