Duoxa1 - dual oxidase maturation factor 1 Gene

Also Known as Nip; Nip1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 213696

Summary

Predicted to enable enzyme binding activity. Acts upstream of or within several processes, including hydrogen peroxide metabolic process; positive regulation of Reactive Oxygen Species metabolic process; and regulation of thyroid hormone generation. Located in plasma membrane. Is expressed in several structures, including brain; genitourinary system; heart; and skeletal muscle. Orthologous to human DUOXA1 (dual oxidase maturation factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Duoxa1 Products (1)

mRNA Protein Name
NM_001305262.1 NP_001292191.1 dual oxidase maturation factor 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
20233719 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within hydrogen peroxide metabolic process IGI
IGI: Inferred from genetic interaction
23770197 MGI
acts upstream of or within positive regulation of neuron differentiation IDA
IDA: Inferred from direct assay
20233719 MGI
acts upstream of or within positive regulation of neuron differentiation IMP
IMP: Inferred from mutant phenotype
20233719 MGI
acts upstream of or within positive regulation of reactive oxygen species metabolic process IGI
IGI: Inferred from genetic interaction
20233719 MGI
acts upstream of or within regulation of inflammatory response IGI
IGI: Inferred from genetic interaction
23770197 MGI
acts upstream of or within regulation of thyroid hormone generation IGI
IGI: Inferred from genetic interaction
22301785 MGI
Cellular Component GO Annotation Evidence References Source
located in plasma membrane IDA
IDA: Inferred from direct assay
20233719 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

dual oxidase maturation factor 1

  • Numb-interacting protein 1

  • dual oxidase activator 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04046 DUOXA1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Duoxa1 NCBI NCBI:90527