2. Gene
  3. Prepl - prolyl endopeptidase-like Gene

Prepl - prolyl endopeptidase-like Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as mKIAA0436; 2810457N15Rik; 9530014L06Rik; D030028O16Rik

Gene ID: 213760 | Gene type: protein coding

About Prepl

Summary

Enables peptidase activity. Involved in Golgi to plasma membrane protein transport and retrograde transport, endosome to Golgi. Located in Golgi apparatus and Cytoskeleton. Colocalizes with trans-Golgi network. Is expressed in several structures, including diaphragm; nervous system; retina; tongue; and vertebral axis musculature. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 22. Orthologous to human PREPL (prolyl endopeptidase like). [provided by Alliance of Genome Resources, Apr 2022]

Prepl Products(4)

mRNA Protein Name
NM_001163622.1 NP_001157094.1 prolyl endopeptidase-like isoform a
NM_001163623.1 NP_001157095.1 prolyl endopeptidase-like isoform b
NM_001163624.1 NP_001157096.1 prolyl endopeptidase-like isoform b
NM_145984.3 NP_666096.3 prolyl endopeptidase-like isoform b
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables peptidase activity IMP
IMP: Inferred from mutant phenotype
21692504 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
23321636 MGI
Biological Process GO Annotation Evidence Reference Source
involved in Golgi to plasma membrane protein transport IMP
IMP: Inferred from mutant phenotype
23321636 MGI
involved in retrograde transport, endosome to Golgi IMP
IMP: Inferred from mutant phenotype
23321636 MGI
Cellular Component GO Annotation Evidence Reference Source
located in Golgi apparatus IDA
IDA: Inferred from direct assay
23485813 MGI
located in cytoskeleton IDA
IDA: Inferred from direct assay
23485813 MGI
colocalizes with trans-Golgi network IMP
IMP: Inferred from mutant phenotype
23321636 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

prolyl endopeptidase-like

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11084 PREPL Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Prepl NCBI NCBI:9581