Tbxa2r - thromboxane A2 receptor Gene
Also Known as TP; TXA2-R
Species: Mus musculus
About Tbxa2r
This gene has 2 transcripts (splice variants), 193 orthologues, 7 paralogues and is associated with 17 phenotypes. Biased expression in thymus adult (RPKM 81.), adrenal adult (RPKM 54.7) and 8 other tissues.
Summary
This gene encodes a multi-pass membrane protein that functions as a G-protein coupled receptor. The encoded protein binds thromboxane A2, resulting in the aggregation of platelets and constriction of blood vessels. Alternative splicing results in multiple transcript variants for this gene. [provided by RefSeq, Mar 2013]
Tbxa2r Products (3)
| mRNA | Protein | Name |
|---|---|---|
| NM_009325.4 | NP_033351.1 | thromboxane A2 receptor |
| NM_001358512.1 | NP_001345441.1 | thromboxane A2 receptor |
| NM_001277265.1 | NP_001264194.1 | thromboxane A2 receptor |
Tbxa2r Protein Structure
7tm_GPCRs: cl28897 (24 - 316)
7tm_GPCRs: cd14964 (26 - 50)
7tm_GPCRs: cd14964 (62 - 84)
7tm_GPCRs: cd14964 (104 - 126)
7tm_GPCRs: cd14964 (148 - 164)
7tm_GPCRs: cd14964 (190 - 213)
7tm_GPCRs: cd14964 (240 - 262)
7tm_GPCRs: cd14964 (283 - 308)
- 0
- 100
- 200
- 300
- 341 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
thromboxane A2 receptor |
|
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-106891 | Domitroban | Antagonist | / | Unkown |
| HY-RS14283 | TBXA2R Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS14284 | Tbxa2r Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS14285 | Tbxa2r Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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