Tbxa2r - thromboxane A2 receptor Gene

Mus musculus

Also known as TP; TXA2-R

Gene ID: 21390 | Gene type: protein coding

About Tbxa2r

Chromosome 10: 81,164,565-81,171,006 forward strand.GRCm39:CM001003.3

This gene has 2 transcripts (splice variants), 193 orthologues, 7 paralogues and is associated with 17 phenotypes. Biased expression in thymus adult (RPKM 81.), adrenal adult (RPKM 54.7) and 8 other tissues.

Summary

This gene encodes a multi-pass membrane protein that functions as a G-protein coupled receptor. The encoded protein binds thromboxane A2, resulting in the aggregation of platelets and constriction of blood vessels. Alternative splicing results in multiple transcript variants for this gene. [provided by RefSeq, Mar 2013]

Tbxa2r Products(3)

mRNA	Protein	Name
NM_009325.4	NP_033351.1	thromboxane A2 receptor
NM_001358512.1	NP_001345441.1	thromboxane A2 receptor
NM_001277265.1	NP_001264194.1	thromboxane A2 receptor

Tbxa2r Protein Structure

7tm_GPCRs

0
100
200
300
341 a.a.

Protein Preferred Names

Protein Names

thromboxane A2 receptor

TXA2 receptor	prostanoid TP receptor
thromboxane prostanoid

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Purity	Rare Diseases
HY-RS14283	TBXA2R Human Pre-designed siRNA Set A	/	Unkown
HY-RS14284	Tbxa2r Mouse Pre-designed siRNA Set A	/	Unkown
HY-RS14285	Tbxa2r Rat Pre-designed siRNA Set A	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Tbxa2r	NCBI	NCBI:6915

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