Sox30 - SRY (sex determining region Y)-box 30 Gene

Mus musculus

Gene ID: 214105 | Gene type: protein coding

About Sox30

Summary

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and DNA-binding transcription repressor activity, RNA polymerase II-specific. Involved in negative regulation of transcription by RNA polymerase II; positive regulation of transcription by RNA polymerase II; and proacrosomal vesicle fusion. Located in chromocenter and nucleus. Is expressed in several structures, including brain; genitourinary system; gut; heart; and lung. Orthologous to human SOX30 (SRY-box transcription factor 30). [provided by Alliance of Genome Resources, Apr 2022]

Sox30 Products(1)

mRNA	Protein	Name
NM_173384.2	NP_775560.1	transcription factor SOX-30

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables DNA-binding transcription activator activity, RNA polymerase II-specific	IMP IMP: Inferred from mutant phenotype	29866902	MGI
enables DNA-binding transcription factor activity	IDA IDA: Inferred from direct assay	29848638	MGI
enables DNA-binding transcription repressor activity, RNA polymerase II-specific	IMP IMP: Inferred from mutant phenotype	29739711	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in negative regulation of transcription by RNA polymerase II	IMP IMP: Inferred from mutant phenotype	29739711	MGI
involved in positive regulation of transcription by RNA polymerase II	IDA IDA: Inferred from direct assay	29848638	MGI
involved in positive regulation of transcription by RNA polymerase II	IMP IMP: Inferred from mutant phenotype	29866902	MGI
involved in proacrosomal vesicle fusion	IMP IMP: Inferred from mutant phenotype	29866902	MGI
involved in spermatid development	IMP IMP: Inferred from mutant phenotype	29848638	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in chromocenter	IDA IDA: Inferred from direct assay	29848638	MGI
located in nucleus	IDA IDA: Inferred from direct assay	29848638	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

transcription factor SOX-30

SRY-box containing gene 30

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13594	SOX30 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS24668	Adam19 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Sox30	NCBI	NCBI:11063

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