Sox30 - SRY (sex determining region Y)-box 30 Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 214105

Summary

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and DNA-binding transcription repressor activity, RNA polymerase II-specific. Involved in negative regulation of transcription by RNA polymerase II; positive regulation of transcription by RNA polymerase II; and proacrosomal vesicle fusion. Located in chromocenter and nucleus. Is expressed in several structures, including brain; genitourinary system; gut; heart; and lung. Orthologous to human SOX30 (SRY-box transcription factor 30). [provided by Alliance of Genome Resources, Apr 2022]

Sox30 Products (1)

mRNA Protein Name
NM_173384.2 NP_775560.1 transcription factor SOX-30

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables DNA-binding transcription activator activity, RNA polymerase II-specific IMP
IMP: Inferred from mutant phenotype
29866902 MGI
enables DNA-binding transcription factor activity IDA
IDA: Inferred from direct assay
29848638 MGI
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IMP
IMP: Inferred from mutant phenotype
29739711 MGI
Biological Process GO Annotation Evidence References Source
involved in negative regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
29739711 MGI
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
29848638 MGI
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
29866902 MGI
involved in proacrosomal vesicle fusion IMP
IMP: Inferred from mutant phenotype
29866902 MGI
involved in spermatid development IMP
IMP: Inferred from mutant phenotype
29848638 MGI
Cellular Component GO Annotation Evidence References Source
located in chromocenter IDA
IDA: Inferred from direct assay
29848638 MGI
located in nucleus IDA
IDA: Inferred from direct assay
29848638 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transcription factor SOX-30

  • SRY-box containing gene 30

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13594 SOX30 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24668 Adam19 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sox30 NCBI NCBI:11063