2. Gene
  3. Tcf20 - transcription factor 20 Gene

Tcf20 - transcription factor 20 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as SPBP; mKIAA0292; 2810438H08Rik

Gene ID: 21411 | Gene type: protein coding

About Tcf20

Summary

Enables DNA-binding transcription factor activity; transcription cis-regulatory region binding activity; and transcription coactivator activity. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including branchial arch; central nervous system; early conceptus; genitourinary system; and sensory organ. Used to study Phelan-McDermid syndrome and autism spectrum disorder. Orthologous to human TCF20 (transcription factor 20). [provided by Alliance of Genome Resources, Apr 2022]

Tcf20 Products(3)

mRNA Protein Name
NM_001114140.1 NP_001107612.1 transcription factor 20 isoform a
NM_001402838.1 NP_001389767.1 transcription factor 20 isoform a
NM_013836.3 NP_038864.3 transcription factor 20 isoform b
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables DNA-binding transcription factor activity IDA
IDA: Inferred from direct assay
7760812 MGI
enables transcription cis-regulatory region binding IDA
IDA: Inferred from direct assay
7760812 MGI
enables transcription coactivator activity IDA
IDA: Inferred from direct assay
10995766 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
7760812 MGI
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
7760812 MGI
Cellular Component GO Annotation Evidence Reference Source
located in nucleus IDA
IDA: Inferred from direct assay
7760812 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transcription factor 20

SPRE-binding protein

TCF-20

nuclear factor SPBP

stromelysin PDGF responsive element binding protein transcription factor

stromelysin-1 PDGF-responsive element-binding protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14302 TCF20 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tcf20 NCBI NCBI:6942