Tdrd5 - tudor domain containing 5 Gene

Mus musculus

Also known as Gm103

Gene ID: 214575 | Gene type: protein coding

About Tdrd5

Summary

Involved in DNA methylation involved in gamete generation; P granule organization; and spermatid development. Located in chromatoid body and pi-body. Is expressed in genitourinary system. Orthologous to human TDRD5 (tudor domain containing 5). [provided by Alliance of Genome Resources, Apr 2022]

Tdrd5 Products(2)

mRNA	Protein	Name
NM_001134741.1	NP_001128213.1	tudor domain-containing protein 5 isoform 1
NM_001277730.1	NP_001264659.1	tudor domain-containing protein 5 isoform 2

Gene Ontology

Biological Process
Cellular Component

Biological Process GO Annotation	Evidence	Reference	Source
involved in P granule organization	IMP IMP: Inferred from mutant phenotype	21383078	MGI
involved in retrotransposon silencing by piRNA-directed DNA methylation	IMP IMP: Inferred from mutant phenotype	21383078	MGI
involved in spermatid development	IMP IMP: Inferred from mutant phenotype	21383078	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in chromatoid body	IDA IDA: Inferred from direct assay	21383078	MGI
located in pi-body	IDA IDA: Inferred from direct assay	21383078	MGI
is active in synapse	EXP EXP: Inferred from Experiment	25211037	MGI
is active in synapse	IDA IDA: Inferred from direct assay	25211037	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

tudor domain-containing protein 5

tudor domain containing protein 5

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14337	TDRD5 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Tdrd5	NCBI	NCBI:163589

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