Senp6 - SUMO/sentrin specific peptidase 6 Gene

Also Known as Susp1; mKIAA0797; 2810017C20Rik; E130319N12Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 215351

Summary

Predicted to enable SUMO-specific endopeptidase activity. Predicted to be involved in protein desumoylation; regulation of kinetochore assembly; and regulation of spindle assembly. Predicted to act upstream of or within proteolysis. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in cytoplasm and nucleus. Is expressed in embryo. Orthologous to human SENP6 (SUMO specific peptidase 6). [provided by Alliance of Genome Resources, Apr 2022]

Senp6 Products (2)

mRNA Protein Name
NM_001311110.1 NP_001298039.1 sentrin-specific protease 6 isoform 1
NM_146003.2 NP_666115.2 sentrin-specific protease 6 isoform 2

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
is active in postsynaptic cytosol IDA
IDA: Inferred from direct assay
33113832 MGI
is active in presynaptic cytosol IDA
IDA: Inferred from direct assay
33113832 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sentrin-specific protease 6

  • SUMO-1-specific protease 1

  • SUMO/sentrin specific protease 6

  • sentrin/SUMO-specific protease SENP6

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12675 SENP6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Senp6 NCBI NCBI:26054