Ncaph - non-SMC condensin I complex, subunit H Gene

Also Known as Brrn1; CAP-H; HCAP-H; mCAP-H; A730011O11Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 215387

Summary

Enables chromatin binding activity. Involved in female meiosis chromosome separation. Acts upstream of or within meiotic chromosome condensation and meiotic chromosome segregation. Located in nucleus. Part of condensin complex. Is active in chromosome. Is expressed in midbrain ventricular layer; nephrogenic zone; olfactory cortex ventricular layer; and telencephalon ventricular layer. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly. Orthologous to human NCAPH (non-SMC condensin I complex subunit H). [provided by Alliance of Genome Resources, Apr 2022]

Ncaph Products (1)

mRNA Protein Name
NM_144818.4 NP_659067.2 condensin complex subunit 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables chromatin binding IDA
IDA: Inferred from direct assay
23531880 MGI
Biological Process GO Annotation Evidence Verweise Source
involved in female meiosis chromosome separation IGI
IGI: Inferred from genetic interaction
25961503 MGI
involved in female meiotic nuclear division IMP
IMP: Inferred from mutant phenotype
25961503 MGI
involved in meiotic chromosome condensation IGI
IGI: Inferred from genetic interaction
25961503 MGI
acts upstream of or within meiotic chromosome condensation IMP
IMP: Inferred from mutant phenotype
21795393 MGI
acts upstream of or within meiotic chromosome segregation IMP
IMP: Inferred from mutant phenotype
21795393 MGI
involved in positive regulation of chromosome segregation IMP
IMP: Inferred from mutant phenotype
25474630 MGI
involved in positive regulation of chromosome separation IMP
IMP: Inferred from mutant phenotype
21795393 MGI
Cellular Component GO Annotation Evidence Verweise Source
is active in chromosome IGI
IGI: Inferred from genetic interaction
25961503 MGI
located in condensed nuclear chromosome IDA
IDA: Inferred from direct assay
25474630 MGI
part of condensin complex IDA
IDA: Inferred from direct assay
21795393 MGI
part of condensin complex IPI
IPI: Inferred from physical interaction
25474630 MGI
is active in nucleus IDA
IDA: Inferred from direct assay
25961503 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

condensin complex subunit 2

  • XCAP-H homolog

  • barren homolog protein 1

  • chromosome-associated protein H

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS09070 NCAPH Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS09071 NCAPH2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ncaph NCBI NCBI:23397