2. Gene
  3. Pomgnt2 - protein O-linked mannose beta 1,4-N-acetylglucosaminyltransferase 2 Gene

Pomgnt2 - protein O-linked mannose beta 1,4-N-acetylglucosaminyltransferase 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Ago61; Gtdc2

Gene ID: 215494 | Gene type: protein coding

About Pomgnt2

Summary

Predicted to enable acetylglucosaminyltransferase activity and protein O-GlcNAc transferase activity. Involved in neuron migration and protein O-linked mannosylation. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in endoplasmic reticulum. Is expressed in brain and eye. Human ortholog(s) of this gene implicated in congenital muscular dystrophy-dystroglycanopathy type A8. Orthologous to human POMGNT2 (protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-)). [provided by Alliance of Genome Resources, Apr 2022]

Pomgnt2 Products(6)

mRNA Protein Name
NM_001289558.2 NP_001276487.1 protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2 precursor
NM_001289559.2 NP_001276488.1 protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2 precursor
NM_001289560.2 NP_001276489.1 protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2 precursor
NM_001408106.1 NP_001395035.1 protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2 precursor
NM_001408107.1 NP_001395036.1 protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2 precursor
NM_153540.5 NP_705768.4 protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2 precursor
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables acetylglucosaminyltransferase activity IMP
IMP: Inferred from mutant phenotype
24256719 MGI
Biological Process GO Annotation Evidence Reference Source
involved in neuron migration IMP
IMP: Inferred from mutant phenotype
24256719 MGI
involved in protein O-linked glycosylation IMP
IMP: Inferred from mutant phenotype
24256719 MGI
involved in protein O-linked mannosylation IMP
IMP: Inferred from mutant phenotype
24256719 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2

glycosyltransferase-like domain containing 2

glycosyltransferase-like domain-containing protein 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10867 POMGNT2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pomgnt2 NCBI NCBI:84892