Rassf2 - Ras association (RalGDS/AF-6) domain family member 2 Gene

Mus musculus

Also known as 3830431H01Rik; 9030412M04Rik

Gene ID: 215653 | Gene type: protein coding

About Rassf2

Summary

Predicted to enable protein kinase activity. Acts upstream of or within several processes, including epidermal growth factor receptor signaling pathway via I-kappaB kinase/NF-kappaB cascade; negative regulation of NIK/NF-kappaB signaling; and regulation of osteoclast differentiation. Located in cytoplasm and nucleus. Is expressed in central nervous system; heart valve; and urinary system. Orthologous to human RASSF2 (Ras association domain family member 2). [provided by Alliance of Genome Resources, Apr 2022]

Rassf2 Products(2)

mRNA	Protein	Name
NM_001362866.1	NP_001349795.1	ras association domain-containing protein 2
NM_175445.4	NP_780654.1	ras association domain-containing protein 2

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	22227519	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within bone remodeling	IMP IMP: Inferred from mutant phenotype	22227519	MGI
acts upstream of or within canonical NF-kappaB signal transduction	IMP IMP: Inferred from mutant phenotype	22227519	MGI
acts upstream of or within homeostasis of number of cells	IMP IMP: Inferred from mutant phenotype	22227519	MGI
acts upstream of or within negative regulation of non-canonical NF-kappaB signal transduction	IMP IMP: Inferred from mutant phenotype	22227519	MGI
acts upstream of or within ossification	IMP IMP: Inferred from mutant phenotype	22227519	MGI
acts upstream of or within regulation of non-canonical NF-kappaB signal transduction	IMP IMP: Inferred from mutant phenotype	22227519	MGI
acts upstream of or within regulation of osteoblast differentiation	IMP IMP: Inferred from mutant phenotype	22227519	MGI
acts upstream of or within regulation of osteoclast differentiation	IMP IMP: Inferred from mutant phenotype	22227519	MGI
acts upstream of or within skeletal system development	IMP IMP: Inferred from mutant phenotype	22227519	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in cytoplasm	IDA IDA: Inferred from direct assay	22227519	MGI
located in nucleus	IDA IDA: Inferred from direct assay	22227519	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

ras association domain-containing protein 2

Ras association (RalGDS/AF-6) domain family 2

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11702	RASSF2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Rassf2	NCBI	NCBI:9770

Name
Email *

	Sorry, but the email address you supplied was invalid.