Rassf2 - Ras association (RalGDS/AF-6) domain family member 2 Gene

Also Known as 3830431H01Rik; 9030412M04Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 215653

Summary

Predicted to enable protein kinase activity. Acts upstream of or within several processes, including epidermal growth factor receptor signaling pathway via I-kappaB kinase/NF-kappaB cascade; negative regulation of NIK/NF-kappaB signaling; and regulation of osteoclast differentiation. Located in cytoplasm and nucleus. Is expressed in central nervous system; heart valve; and urinary system. Orthologous to human RASSF2 (Ras association domain family member 2). [provided by Alliance of Genome Resources, Apr 2022]

Rassf2 Products (2)

mRNA Protein Name
NM_001362866.1 NP_001349795.1 ras association domain-containing protein 2
NM_175445.4 NP_780654.1 ras association domain-containing protein 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
22227519 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within bone remodeling IMP
IMP: Inferred from mutant phenotype
22227519 MGI
acts upstream of or within canonical NF-kappaB signal transduction IMP
IMP: Inferred from mutant phenotype
22227519 MGI
acts upstream of or within homeostasis of number of cells IMP
IMP: Inferred from mutant phenotype
22227519 MGI
acts upstream of or within negative regulation of non-canonical NF-kappaB signal transduction IMP
IMP: Inferred from mutant phenotype
22227519 MGI
acts upstream of or within ossification IMP
IMP: Inferred from mutant phenotype
22227519 MGI
acts upstream of or within regulation of non-canonical NF-kappaB signal transduction IMP
IMP: Inferred from mutant phenotype
22227519 MGI
acts upstream of or within regulation of osteoblast differentiation IMP
IMP: Inferred from mutant phenotype
22227519 MGI
acts upstream of or within regulation of osteoclast differentiation IMP
IMP: Inferred from mutant phenotype
22227519 MGI
acts upstream of or within skeletal system development IMP
IMP: Inferred from mutant phenotype
22227519 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
22227519 MGI
located in nucleus IDA
IDA: Inferred from direct assay
22227519 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ras association domain-containing protein 2

  • Ras association (RalGDS/AF-6) domain family 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11702 RASSF2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rassf2 NCBI NCBI:9770