Stox1 - storkhead box 1 Gene

Also Known as Gm63; 4732470K04Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 216021

Summary

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including positive regulation of epithelial cell proliferation; positive regulation of otic vesicle morphogenesis; and positive regulation of protein kinase B signaling. Located in cell cortex and nucleus. Human ortholog(s) of this gene implicated in pre-eclampsia. Orthologous to human STOX1 (storkhead box 1). [provided by Alliance of Genome Resources, Apr 2022]

Stox1 Products (2)

mRNA Protein Name
NM_001033260.2 NP_001028432.1 storkhead-box protein 1 isoform 1
NM_001364705.1 NP_001351634.1 storkhead-box protein 1 isoform 2

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in inner ear development IDA
IDA: Inferred from direct assay
25677106 MGI
involved in positive regulation of cell cycle IMP
IMP: Inferred from mutant phenotype
25677106 MGI
involved in positive regulation of otic vesicle morphogenesis IMP
IMP: Inferred from mutant phenotype
25677106 MGI
involved in positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IMP
IMP: Inferred from mutant phenotype
25677106 MGI
involved in regulation of mitotic cell cycle IMP
IMP: Inferred from mutant phenotype
25677106 MGI
Cellular Component GO Annotation Evidence References Source
located in cell cortex IDA
IDA: Inferred from direct assay
25677106 MGI
located in nucleus IDA
IDA: Inferred from direct assay
25677106 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

storkhead-box protein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13954 STOX1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Stox1 NCBI NCBI:219736