Ctnna3 - catenin (cadherin associated protein), alpha 3 Gene

Also Known as Vr22; Catna3; 4933408A16; 4930429L08Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 216033

Summary

Predicted to enable actin filament binding activity and beta-catenin binding activity. Involved in cell-cell adhesion. Located in adherens junction; fascia adherens; and lamellipodium. Is expressed in cardiac muscle tissue and skin of male preputial swelling. Human ortholog(s) of this gene implicated in arrhythmogenic right ventricular dysplasia 13. Orthologous to human CTNNA3 (catenin alpha 3). [provided by Alliance of Genome Resources, Apr 2022]

Ctnna3 Products (3)

mRNA Protein Name
NM_001164376.1 NP_001157848.1 catenin alpha-3 isoform 1
NM_001164519.1 NP_001157991.1 catenin alpha-3 isoform 2
NM_177612.3 NP_808280.2 catenin alpha-3 isoform 1
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
11590244 MGI
Biological Process GO Annotation Evidence References Source
involved in cell-cell adhesion IDA
IDA: Inferred from direct assay
11590244 MGI
Cellular Component GO Annotation Evidence References Source
located in adherens junction IDA
IDA: Inferred from direct assay
19129494 MGI
located in fascia adherens IDA
IDA: Inferred from direct assay
17535849 MGI
located in lamellipodium IDA
IDA: Inferred from direct assay
14657280 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

catenin alpha-3

  • alpha T-catenin

  • alpha-catenin-like protein

  • alphaT-catenin

  • cadherin-associated protein

Orthologs Information

Species Symbol Source ID
Homo sapiens Ctnna3 NCBI NCBI:29119