Tmem259 - transmembrane protein 259 Gene

Also Known as ORF61; R32184_3; mFLJ00277; AC087114.7gm2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 216157

Summary

Involved in negative regulation of neuron death; positive regulation of ERAD pathway; and response to endoplasmic reticulum stress. Located in endoplasmic reticulum. Orthologous to human TMEM259 (transmembrane protein 259). [provided by Alliance of Genome Resources, Apr 2022]

Tmem259 Products (2)

mRNA Protein Name
NM_001003949.4 NP_001003949.2 membralin isoform 2
NM_001359632.1 NP_001346561.1 membralin isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25977983 MGI
Biological Process GO Annotation Evidence References Source
involved in positive regulation of ERAD pathway IDA
IDA: Inferred from direct assay
25977983 MGI
involved in response to endoplasmic reticulum stress IMP
IMP: Inferred from mutant phenotype
25977983 MGI
Cellular Component GO Annotation Evidence References Source
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
25977983 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

membralin

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14712 TMEM259 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tmem259 NCBI NCBI:91304