2. Gene
  3. Sbno2 - strawberry notch 2 Gene

Sbno2 - strawberry notch 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Sno; Stno; F730040C21

Gene ID: 216161 | Gene type: protein coding

About Sbno2

Summary

Predicted to enable chromatin DNA binding activity and histone binding activity. Involved in several processes, including cellular response to cytokine stimulus; cellular response to lipopolysaccharide; and macrophage activation involved in immune response. Acts upstream of or within several processes, including bone mineralization; bone trabecula morphogenesis; and osteoclast fusion. Predicted to be active in nucleus. Is expressed in submandibular gland primordium and vibrissa. Orthologous to human SBNO2 (strawberry Notch homolog 2). [provided by Alliance of Genome Resources, Apr 2022]

Sbno2 Products(4)

mRNA Protein Name
NM_001359635.1 NP_001346564.1 protein strawberry notch homolog 2 isoform 2
NM_001359636.1 NP_001346565.1 protein strawberry notch homolog 2 isoform 3
NM_001359637.1 NP_001346566.1 protein strawberry notch homolog 2 isoform 4
NM_183426.2 NP_906271.1 protein strawberry notch homolog 2 isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
23980096 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within bone mineralization IMP
IMP: Inferred from mutant phenotype
23980096 MGI
acts upstream of or within bone trabecula morphogenesis IMP
IMP: Inferred from mutant phenotype
23980096 MGI
involved in cellular response to interleukin-11 IDA
IDA: Inferred from direct assay
25903009 MGI
involved in cellular response to interleukin-6 IDA
IDA: Inferred from direct assay
25903009 MGI
involved in cellular response to leukemia inhibitory factor IDA
IDA: Inferred from direct assay
25903009 MGI
involved in cellular response to lipopolysaccharide IDA
IDA: Inferred from direct assay
25903009 MGI
involved in macrophage activation involved in immune response IMP
IMP: Inferred from mutant phenotype
18025162 MGI
acts upstream of or within multinuclear osteoclast differentiation IMP
IMP: Inferred from mutant phenotype
23980096 MGI
involved in negative regulation of DNA-templated transcription IMP
IMP: Inferred from mutant phenotype
18025162 MGI
acts upstream of or within osteoclast differentiation IMP
IMP: Inferred from mutant phenotype
23980096 MGI
acts upstream of or within osteoclast fusion IMP
IMP: Inferred from mutant phenotype
23980096 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
23980096 MGI
involved in regulation of inflammatory response IMP
IMP: Inferred from mutant phenotype
18025162 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein strawberry notch homolog 2

strawberry notch homolog 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12470 SBNO2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sbno2 NCBI NCBI:22904