Alx1 - ALX homeobox 1 Gene

Also Known as Cart1; C130005I02

Species: Mus musculus

Gene Type: protein coding
Gene ID: 216285

Summary

Enables DNA-binding transcription factor activity and sequence-specific DNA binding activity. Acts upstream of or within several processes, including embryonic morphogenesis; mesenchymal cell development; and roof of mouth development. Located in nucleus. Part of transcription regulator complex. Is expressed in several structures, including branchial arch; embryo mesenchyme; genitourinary system; limb primordium; and nose. Orthologous to human ALX1 (ALX homeobox 1). [provided by Alliance of Genome Resources, Apr 2022]

Alx1 Products (1)

mRNA Protein Name
NM_172553.4 NP_766141.1 ALX homeobox protein 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables DNA-binding transcription factor activity IDA
IDA: Inferred from direct assay
9847249 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
9847249 MGI
enables sequence-specific DNA binding IDA
IDA: Inferred from direct assay
9847249 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within anterior/posterior pattern specification IGI
IGI: Inferred from genetic interaction
9847249 MGI
acts upstream of or within embryonic limb morphogenesis IGI
IGI: Inferred from genetic interaction
9847249 MGI
acts upstream of or within embryonic skeletal system morphogenesis IGI
IGI: Inferred from genetic interaction
9847249 MGI
acts upstream of or within mesenchymal cell development IMP
IMP: Inferred from mutant phenotype
8673125 MGI
acts upstream of or within neural tube closure IMP
IMP: Inferred from mutant phenotype
8673125 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
9847249 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IGI
IGI: Inferred from genetic interaction
9847249 MGI
acts upstream of or within roof of mouth development IGI
IGI: Inferred from genetic interaction
9847249 MGI
acts upstream of or within stem cell development IMP
IMP: Inferred from mutant phenotype
8673125 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
12929931 MGI
part of transcription regulator complex IDA
IDA: Inferred from direct assay
9847249 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ALX homeobox protein 1

  • cartilage homeoprotein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00636 ALX1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Alx1 NCBI NCBI:8092