2. Gene
  3. Rufy1 - RUN and FYVE domain containing 1 Gene

Rufy1 - RUN and FYVE domain containing 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Rabip4; ZFYVE12; 3000002E04Rik

Gene ID: 216724 | Gene type: protein coding

About Rufy1

Summary

Predicted to enable SH2 domain binding activity; SH3 domain binding activity; and identical protein binding activity. Acts upstream of or within protein transport; regulation of endocytosis; and small GTPase mediated signal transduction. Located in cytoplasm. Is expressed in brain; female associated reproductive structure; male associated reproductive structure; ovary; and testis. Orthologous to human RUFY1 (RUN and FYVE domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]

Rufy1 Products(1)

mRNA Protein Name
NM_172557.3 NP_766145.1 RUN and FYVE domain-containing protein 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
11172003 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within protein transport IDA
IDA: Inferred from direct assay
11172003 MGI
acts upstream of or within regulation of endocytosis IDA
IDA: Inferred from direct assay
11172003 MGI
acts upstream of or within small GTPase-mediated signal transduction IDA
IDA: Inferred from direct assay
11172003 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
11172003 MGI
NOT located in cytosol IDA
IDA: Inferred from direct assay
11172003 MGI
NOT located in late endosome IDA
IDA: Inferred from direct assay
11172003 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

RUN and FYVE domain-containing protein 1

FYVE-finger containing protein

Rab4a interacting protein

rab4-interacting protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12344 RUFY1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rufy1 NCBI NCBI:80230