Tecta - tectorin alpha Gene
Also Known as Tctna
Species: Mus musculus
Summary
An extracellular matrix structural constituent. Predicted to be involved in cell-matrix adhesion. Predicted to act upstream of or within sensory perception of sound. Located in extracellular matrix. Is expressed in inner ear. Used to study autosomal dominant nonsyndromic deafness 12. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 12; autosomal recessive nonsyndromic deafness 21; and sensorineural hearing loss. Orthologous to human TECTA (tectorin alpha). [provided by Alliance of Genome Resources, Apr 2022]
Tecta Products (3)
| mRNA | Protein | Name |
|---|---|---|
| NM_001324548.2 | NP_001311477.1 | alpha-tectorin isoform 2 preproprotein |
| NM_001378602.1 | NP_001365531.1 | alpha-tectorin isoform 1 prepreprotein precursor |
| NM_009347.4 | NP_033373.2 | alpha-tectorin isoform 1 preproprotein |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables extracellular matrix structural constituent |
IDA
IDA: Inferred from direct assay
|
9079715 | MGI |
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
21368133 | MGI |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| acts upstream of or within auditory receptor cell stereocilium organization |
IGI
IGI: Inferred from genetic interaction
|
30801007 | MGI |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| located in extracellular matrix |
IDA
IDA: Inferred from direct assay
|
9079715 | MGI |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
alpha-tectorin |
|