Tmem106a - transmembrane protein 106A Gene

Also Known as 0610008L10Rik

Species: Mus musculus

Gene Type: protein coding

Gene ID: 217203

Summary

Involved in several processes, including glycoprotein biosynthetic process; positive regulation of cytokine production; and positive regulation of intracellular signal transduction. Located in plasma membrane. Orthologous to human TMEM106A (transmembrane protein 106A). [provided by Alliance of Genome Resources, Apr 2022]

Tmem106a Products (4)

mRNA	Protein	Name
NM_001359325.1	NP_001346254.1	transmembrane protein 106A
NM_001359326.1	NP_001346255.1	transmembrane protein 106A
NM_001359327.1	NP_001346256.1	transmembrane protein 106A
NM_144830.3	NP_659079.1	transmembrane protein 106A

Gene Ontology

Biological Process
Cellular Component

Biological Process GO Annotation	Evidence	References	Source
involved in CD80 biosynthetic process	IDA IDA: Inferred from direct assay	26215746	MGI
involved in CD86 biosynthetic process	IDA IDA: Inferred from direct assay	26215746	MGI
involved in macrophage activation	IDA IDA: Inferred from direct assay	26215746	MGI
involved in positive regulation of MAPK cascade	IDA IDA: Inferred from direct assay	26215746	MGI
involved in positive regulation of MHC class II biosynthetic process	IDA IDA: Inferred from direct assay	26215746	MGI
involved in positive regulation of canonical NF-kappaB signal transduction	IDA IDA: Inferred from direct assay	26215746	MGI
involved in positive regulation of interleukin-1 beta production	IDA IDA: Inferred from direct assay	26215746	MGI
involved in positive regulation of interleukin-6 production	IDA IDA: Inferred from direct assay	26215746	MGI
involved in positive regulation of nitric oxide metabolic process	IDA IDA: Inferred from direct assay	26215746	MGI
involved in positive regulation of tumor necrosis factor production	IDA IDA: Inferred from direct assay	26215746	MGI

Cellular Component GO Annotation	Evidence	References	Source
located in plasma membrane	IDA IDA: Inferred from direct assay	26215746	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names	Protein Names
transmembrane protein 106A

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14645	TMEM106A Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Tmem106a	NCBI	NCBI:113277