2. Gene
  3. Abca5 - ATP-binding cassette, sub-family A (ABC1), member 5 Gene

Abca5 - ATP-binding cassette, sub-family A (ABC1), member 5 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as ABC13; mKIAA1888; B930033A02Rik

Gene ID: 217265 | Gene type: protein coding

About Abca5

Summary

Predicted to enable ATPase-coupled transmembrane transporter activity and lipid transporter activity. Involved in several processes, including Cholesterol efflux; negative regulation of macrophage derived foam cell differentiation; and regulation of Cholesterol transport. Located in late endosome and lysosome. Orthologous to human ABCA5 (ATP binding cassette subfamily A member 5). [provided by Alliance of Genome Resources, Apr 2022]

Abca5 Products(1)

mRNA Protein Name
NM_147219.2 NP_671752.2 cholesterol transporter ABCA5
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in cholesterol efflux IMP
IMP: Inferred from mutant phenotype
20382126 MGI
involved in high-density lipoprotein particle remodeling IMP
IMP: Inferred from mutant phenotype
20382126 MGI
involved in negative regulation of macrophage derived foam cell differentiation IMP
IMP: Inferred from mutant phenotype
20382126 MGI
involved in positive regulation of reverse cholesterol transport IMP
IMP: Inferred from mutant phenotype
32687853 MGI
involved in regulation of cholesterol efflux IMP
IMP: Inferred from mutant phenotype
32687853 MGI
Cellular Component GO Annotation Evidence Reference Source
located in late endosome IDA
IDA: Inferred from direct assay
15870284 MGI
located in lysosome IDA
IDA: Inferred from direct assay
15870284 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cholesterol transporter ABCA5

ATP-binding cassette sub-family A member 5

ATP-binding cassette transporter sub-family A member 5

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00043 ABCA5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Abca5 NCBI NCBI:23461