Ppp2r5d - protein phosphatase 2, regulatory subunit B', delta Gene

Mus musculus

Also known as Tex271; B'delta; TEG-271

Gene ID: 21770 | Gene type: protein coding

About Ppp2r5d

Summary

Predicted to enable phosphoprotein Phosphatase activity and protein Phosphatase activator activity. Acts upstream of or within positive regulation of protein dephosphorylation. Predicted to be part of protein Phosphatase type 2A complex. Predicted to be active in cytosol and nucleus. Is expressed in several structures, including brain; ovary; and spleen. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability 35. Orthologous to human PPP2R5D (protein Phosphatase 2 regulatory subunit B'delta). [provided by Alliance of Genome Resources, Apr 2022]

Ppp2r5d Products(2)

mRNA	Protein	Name
NM_001357684.1	NP_001344613.1	serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform isoform 2
NM_009358.3	NP_033384.2	serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform isoform 1

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	19029245	MGI
enables protein phosphatase activator activity	IDA IDA: Inferred from direct assay	18496528	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform

testis expressed gene 271

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11021	PPP2R5D Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Ppp2r5d	NCBI	NCBI:5528

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