B4galt7 - xylosylprotein beta1,4-galactosyltransferase, polypeptide 7 (galactosyltransferase I) Gene

Also Known as XGPT; XGalT-1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 218271

Summary

Predicted to enable beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity; manganese ion binding activity; and xylosylprotein 4-beta-galactosyltransferase activity. Predicted to be involved in several processes, including glycoprotein biosynthetic process; glycosaminoglycan biosynthetic process; and negative regulation of fibroblast proliferation. Predicted to be integral component of membrane. Predicted to be active in Golgi apparatus. Is expressed in several structures, including central nervous system and retina. Human ortholog(s) of this gene implicated in Ehlers-Danlos syndrome and Ehlers-Danlos syndrome spondylodysplastic type 1. Orthologous to human B4GALT7 (beta-1,4-galactosyltransferase 7). [provided by Alliance of Genome Resources, Apr 2022]

B4galt7 Products (2)

mRNA Protein Name
NM_001311137.1 NP_001298066.1 beta-1,4-galactosyltransferase 7 isoform 2
NM_146045.2 NP_666157.1 beta-1,4-galactosyltransferase 7 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables xylosylprotein 4-beta-galactosyltransferase activity IMP
IMP: Inferred from mutant phenotype
20809901 MGI
Biological Process GO Annotation Evidence References Source
involved in glycosaminoglycan biosynthetic process IMP
IMP: Inferred from mutant phenotype
20809901 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

beta-1,4-galactosyltransferase 7

  • UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 7

  • UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 7

  • UDP-galactose:beta-xylose beta-1,4-galactosyltransferase

  • b4Gal-T7

  • beta-1,4-GalTase 7

  • beta4Gal-T7

  • proteoglycan UDP-galactose:

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-E70138 β-1,4-Galactosyltransferase 7 / Unkown
HY-RS01325 B4GALT7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens B4galt7 NCBI NCBI:11285