Marveld2 - MARVEL (membrane-associating) domain containing 2 Gene

Also Known as Tric; Trica; Tricb; Tricc; MARVD2; Mrvldc2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 218518

Summary

Acts upstream of or within cell-cell junction organization and sensory perception of sound. Located in Schmidt-Lanterman incisure; paranodal junction; and tight junction. Is expressed in several structures, including brain; genitourinary system; gut; immune system; and sensory organ. Used to study autosomal recessive nonsyndromic deafness 49. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 49. Orthologous to human MARVELD2 (MARVEL domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]

Marveld2 Products (2)

mRNA Protein Name
NM_001038602.4 NP_001033691.1 MARVEL domain-containing protein 2 isoform 1
NM_178410.3 NP_848497.2 MARVEL domain-containing protein 2 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
23239027 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cell-cell junction organization IMP
IMP: Inferred from mutant phenotype
16365161 MGI
acts upstream of or within sensory perception of sound IMP
IMP: Inferred from mutant phenotype
23979167 MGI
Cellular Component GO Annotation Evidence References Source
located in Schmidt-Lanterman incisure IDA
IDA: Inferred from direct assay
21097846 MGI
located in bicellular tight junction IDA
IDA: Inferred from direct assay
16365161 MGI
located in paranodal junction IDA
IDA: Inferred from direct assay
21097846 MGI
located in tight junction IDA
IDA: Inferred from direct assay
23239027 MGI
located in tricellular tight junction IDA
IDA: Inferred from direct assay
16365161 MGI
located in tricellular tight junction IMP
IMP: Inferred from mutant phenotype
25217574 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

MARVEL domain-containing protein 2

  • tricellulin

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08155 MARVELD2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Marveld2 NCBI NCBI:153562