Polr3a - polymerase (RNA) III (DNA directed) polypeptide A Gene

Mus musculus

Also known as RPC1; RPC155; 9330175N20Rik

Gene ID: 218832 | Gene type: protein coding

About Polr3a

Summary

Enables chromatin binding activity. Predicted to be involved in innate immune response and positive regulation of interferon-beta production. Predicted to be located in nucleoplasm. Predicted to be part of RNA polymerase III complex. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy 7 with or without oligodontia and-or hypogonadotropic hypogonadism and progeria. Orthologous to human POLR3A (RNA polymerase III subunit A). [provided by Alliance of Genome Resources, Apr 2022]

Polr3a Products(1)

mRNA	Protein	Name
NM_001081247.2	NP_001074716.1	DNA-directed RNA polymerase III subunit RPC1

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables chromatin binding	IDA IDA: Inferred from direct assay	22287103	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

DNA-directed RNA polymerase III subunit RPC1

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10855	POLR3A Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Polr3a	NCBI	NCBI:11128

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