2. Gene
  3. Wapl - WAPL cohesin release factor Gene

Wapl - WAPL cohesin release factor Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as FOE; DIF-2; Wapal; A530089A20Rik

Gene ID: 218914 | Gene type: protein coding

About Wapl

Summary

Studies suggest that the protein encoded by this gene is important for the release of cohesin from chromatin. This gene product is thought to be essential for development, and reduced expression of this gene in cells causes defects in chromatin structure. High levels of expression of the human ortholog of this gene are observed in cervical cancers, and expression of the human ortholog of this gene in mice results in tumor formation. Alternative splicing results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Aug 2014]

Wapl Products(2)

mRNA Protein Name
NM_001004436.4 NP_001004436.2 wings apart-like protein homolog isoform 1
NM_001301330.1 NP_001288259.1 wings apart-like protein homolog isoform 2
Protein Preferred Names Protein Names

wings apart-like protein homolog

dioxin-inducible factor 2

friend of EBNA2

wings apart-like homolog

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15738 WAPL Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Wapl NCBI NCBI:23063