Tmod1 - tropomodulin 1 Gene

Also Known as Tmod; E-Tmod

Species: Mus musculus

Gene Type: protein coding
Gene ID: 21916

Summary

Enables tropomyosin binding activity. Involved in lens fiber cell development. Acts upstream of or within adult locomotory behavior; muscle contraction; and myofibril assembly. Located in cortical cytoskeleton; membrane; and sarcomere. Is expressed in several structures, including ganglia; heart; hemolymphoid system; musculature; and sensory organ. Used to study dilated cardiomyopathy. Orthologous to human TMOD1 (tropomodulin 1). [provided by Alliance of Genome Resources, Apr 2022]

Tmod1 Products (1)

mRNA Protein Name
NM_021883.2 NP_068683.1 tropomodulin-1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables tropomyosin binding IDA
IDA: Inferred from direct assay
20368620 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within adult locomotory behavior IMP
IMP: Inferred from mutant phenotype
20368620 MGI
involved in lens fiber cell development IGI
IGI: Inferred from genetic interaction
23144950 MGI
acts upstream of or within muscle contraction IMP
IMP: Inferred from mutant phenotype
20368620 MGI
acts upstream of or within myofibril assembly IMP
IMP: Inferred from mutant phenotype
14657235 MGI
NOT acts upstream of or within skeletal muscle myosin thick filament assembly IMP
IMP: Inferred from mutant phenotype
14657235 MGI
Cellular Component GO Annotation Evidence References Source
located in cortical cytoskeleton IDA
IDA: Inferred from direct assay
18723693 MGI
located in membrane IDA
IDA: Inferred from direct assay
18723693 MGI
located in myofibril IDA
IDA: Inferred from direct assay
14657235 MGI
located in sarcomere IDA
IDA: Inferred from direct assay
24840128 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tropomodulin-1

  • erythrocyte tropomodulin

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14759 TMOD1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22864 Tmod1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tmod1 NCBI NCBI:7111