AK9 - adenylate kinase 9 Gene

Homo sapiens

Also known as AK 9; AKD1; AKD2; C6orf199; C6orf224; dJ70A9.1

Gene ID: 221264 | Gene type: protein coding

About AK9

Cytogenetic location: 6q21 Genomic coordinates (GRCh38): 6:109,492,855-109,691,202 (from NCBI)

This gene has 12 transcripts (splice variants), 184 orthologues, 9 paralogues and is associated with 1 phenotype. Broad expression in testis (RPKM 4.3), thyroid (RPKM 0.9) and 23 other tissues.

Summary

The protein encoded by this gene catalyzes the interconversion of nucleosides, possessing both nucleoside monophosphate and diphosphate kinase activities. The encoded protein uses these interconversions to maintain nucleoside homeostasis. [provided by RefSeq, Jul 2016]

AK9 Products(4)

mRNA	Protein	Name
NM_001145128.3	NP_001138600.2	adenylate kinase 9 isoform 1
NM_001329602.2	NP_001316531.1	adenylate kinase 9 isoform 2
NM_001329603.2	NP_001316532.1	adenylate kinase 9 isoform 3
NM_145025.5	NP_659462.1	adenylate kinase 9 isoform 2

AK9 Protein Structure

ADK

YHS

ADK

0
300
600
900
1200
1500
1800
1911 a.a.

Protein Preferred Names

Protein Names

adenylate kinase 9

adenylate kinase domain containing 1

Related Diseases

Diseases

Alias

Postsynaptic Congenital Myasthenic Syndromes

Congenital Myasthenic Syndromes, Postsynaptic

Reticular Dysgenesis

Severe Combined Immunodeficiency With Leukopenia	De Vaal Disease
Congenital Aleukia	Aleukocytosis
Hematopoietic Hypoplasia, Generalized	Reticular Dysgenesia
Devaal Disease	Rd
Ak2 Deficiency	Congenital Aleukocytosis
Generalized Hematopoietic Hypoplasia	Scid With Leukopenia
RDYS

Congenital Myasthenic Syndrome

Congenital Myasthenia	Congenital Myasthenic Syndromes
Cms	Myasthenic Syndromes, Congenital
Myasthenic Syndromes Congenital	Myasthenic Syndrome, Congenital
Congenital Myasthenic Syndrome Ib	Congenital And Developmental Myasthenia
Developmental Myasthenia

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00511	AK9 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	AK9	VGNC	VGNC:81017
Rattus norvegicus	AK9	RGD	RGD:1559879
Mus musculus	AK9	MGD	MGI:2685080
Bos taurus	AK9	VGNC	VGNC:25778
Canis familiaris	AK9	VGNC	VGNC:37750